ATP Alters the Diffusion Mechanics of MutS on Mismatched DNA

The mismatch repair (MMR) initiation protein MutS forms at least two types of sliding clamps on DNA: a transient mismatch searching clamp (~1 s) and an unusually stable (~600 s) ATP-bound clamp that recruits downstream MMR components. Remarkably, direct visualization of single MutS particles on mism...

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Main Authors: Cho, Won-Ki, Jeong, Cherlhyun, Kim, Daehyung, Chang, Minhyeok, Song, Kyung-Mi, Hanne, Jeungphill, Ban, Changill, Fishel, Richard, Lee, Jong-Bong
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974879/
https://ncbi.nlm.nih.gov/pubmed/22682745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.04.017
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