ATP Alters the Diffusion Mechanics of MutS on Mismatched DNA

The mismatch repair (MMR) initiation protein MutS forms at least two types of sliding clamps on DNA: a transient mismatch searching clamp (~1 s) and an unusually stable (~600 s) ATP-bound clamp that recruits downstream MMR components. Remarkably, direct visualization of single MutS particles on mism...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Cho, Won-Ki, Jeong, Cherlhyun, Kim, Daehyung, Chang, Minhyeok, Song, Kyung-Mi, Hanne, Jeungphill, Ban, Changill, Fishel, Richard, Lee, Jong-Bong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974879/
https://ncbi.nlm.nih.gov/pubmed/22682745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.04.017
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi