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Rax-CreER(T2) Knock-In Mice: A Tool for Selective and Conditional Gene Deletion in Progenitor Cells and Radial Glia of the Retina and Hypothalamus

To study gene function in neural progenitors and radial glia of the retina and hypothalamus, we developed a Rax-CreER(T2) mouse line in which a tamoxifen-inducible Cre recombinase is inserted into the endogenous Rax locus. By crossing Rax-CreER(T2) with the Cre-dependent Ai9 reporter line, we demons...

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Hlavní autoři: Pak, Thomas, Yoo, Sooyeon, Miranda-Angulo, Ana M., Wang, Hong, Blackshaw, Seth
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974648/
https://ncbi.nlm.nih.gov/pubmed/24699247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090381
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