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Rax-CreER(T2) Knock-In Mice: A Tool for Selective and Conditional Gene Deletion in Progenitor Cells and Radial Glia of the Retina and Hypothalamus
To study gene function in neural progenitors and radial glia of the retina and hypothalamus, we developed a Rax-CreER(T2) mouse line in which a tamoxifen-inducible Cre recombinase is inserted into the endogenous Rax locus. By crossing Rax-CreER(T2) with the Cre-dependent Ai9 reporter line, we demons...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3974648/ https://ncbi.nlm.nih.gov/pubmed/24699247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090381 |
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