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Molecular insights into the membrane-associated phosphatidylinositol 4-kinase IIα
Phosphatidylinositol 4-kinase IIα (PI4KIIα), a membrane-associated PI kinase, plays a central role in cell signalling and trafficking. Its kinase activity critically depends on palmitoylation of its cysteine-rich motif (-CCPCC-) and is modulated by the membrane environment. Lack of atomic structure...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Pub. Group
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3974213/ https://ncbi.nlm.nih.gov/pubmed/24675427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4552 |
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