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Thiabendazole inhibits ubiquinone reduction activity of mitochondrial respiratory complex II via a water molecule mediated binding feature

The mitochondrial respiratory complex II or succinate: ubiquinone oxidoreductase (SQR) is a key membrane complex in both the tricarboxylic acid cycle and aerobic respiration. Five disinfectant compounds were investigated with their potent inhibition effects on the ubiquinone reduction activity of th...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Zhou, Qiangjun, Zhai, Yujia, Lou, Jizhong, Liu, Man, Pang, Xiaoyun, Sun, Fei
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875242/
https://ncbi.nlm.nih.gov/pubmed/21822798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1079-1
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