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Oxygen and the copper chaperone CCS regulate posttranslational activation of Cu,Zn superoxide dismutase
Oxidative stress leads to the up-regulation of many antioxidant enzymes including Cu,Zn superoxide dismutase (SOD1) via transcriptional mechanisms; however, few examples of posttranslational regulation are known. The copper chaperone for SOD1 (CCS) is involved in physiological SOD1 activation, and i...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397415/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15064408/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401175101 |
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