An Induced Pluripotent Stem Cell Model of Hypoplastic Left Heart Syndrome (HLHS) Reveals Multiple Expression and Functional Differences in HLHS-Derived Cardiac Myocytes

Hypoplastic left heart syndrome (HLHS) is a serious congenital cardiovascular malformation resulting in hypoplasia or atresia of the left ventricle, ascending aorta, and aortic and mitral valves. Diminished flow through the left side of the heart is clearly a key contributor to the condition, but an...

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Autori principali: Jiang, Yan, Habibollah, Saba, Tilgner, Katarzyna, Collin, Joseph, Barta, Tomas, Al-Aama, Jumana Yousuf, Tesarov, Lenka, Hussain, Rafiqul, Trafford, Andrew W., Kirkwood, Graham, Sernagor, Evelyne, Eleftheriou, Cyril G., Przyborski, Stefan, Stojković, Miodrag, Lako, Majlinda, Keavney, Bernard, Armstrong, Lyle
Natura: Artigo
Lingua:Inglês
Pubblicazione: AlphaMed Press 2014
Soggetti:
Embryonic Stem Cells/Induced Pluripotent Stem (iPS) Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973710/
https://ncbi.nlm.nih.gov/pubmed/24591732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2013-0105
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