An Induced Pluripotent Stem Cell Model of Hypoplastic Left Heart Syndrome (HLHS) Reveals Multiple Expression and Functional Differences in HLHS-Derived Cardiac Myocytes

Hypoplastic left heart syndrome (HLHS) is a serious congenital cardiovascular malformation resulting in hypoplasia or atresia of the left ventricle, ascending aorta, and aortic and mitral valves. Diminished flow through the left side of the heart is clearly a key contributor to the condition, but an...

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Main Authors: Jiang, Yan, Habibollah, Saba, Tilgner, Katarzyna, Collin, Joseph, Barta, Tomas, Al-Aama, Jumana Yousuf, Tesarov, Lenka, Hussain, Rafiqul, Trafford, Andrew W., Kirkwood, Graham, Sernagor, Evelyne, Eleftheriou, Cyril G., Przyborski, Stefan, Stojković, Miodrag, Lako, Majlinda, Keavney, Bernard, Armstrong, Lyle
Format: Artigo
Jezik:Inglês
Izdano: AlphaMed Press 2014
Teme:
Embryonic Stem Cells/Induced Pluripotent Stem (iPS) Cells
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973710/
https://ncbi.nlm.nih.gov/pubmed/24591732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2013-0105
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