G Protein–Coupled Receptor Oligomerization Revisited: Functional and Pharmacological Perspectives

Most evidence indicates that, as for family C G protein–coupled receptors (GPCRs), family A GPCRs form homo- and heteromers. Homodimers seem to be a predominant species, with potential dynamic formation of higher-order oligomers, particularly tetramers. Although monomeric GPCRs can activate G protei...

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מידע ביבליוגרפי
Main Authors: Ferré, Sergi, Casadó, Vicent, Devi, Lakshmi A., Filizola, Marta, Jockers, Ralf, Lohse, Martin J., Milligan, Graeme, Pin, Jean-Philippe, Guitart, Xavier
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Pharmacology and Experimental Therapeutics 2014
נושאים:
Review Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973609/
https://ncbi.nlm.nih.gov/pubmed/24515647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.113.008052
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