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G Protein–Coupled Receptor Oligomerization Revisited: Functional and Pharmacological Perspectives
Most evidence indicates that, as for family C G protein–coupled receptors (GPCRs), family A GPCRs form homo- and heteromers. Homodimers seem to be a predominant species, with potential dynamic formation of higher-order oligomers, particularly tetramers. Although monomeric GPCRs can activate G protei...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973609/ https://ncbi.nlm.nih.gov/pubmed/24515647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.113.008052 |
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