Activation of Mu Opioid Receptors Sensitizes Transient Receptor Potential Vanilloid Type 1 (TRPV1) via β-Arrestin-2-Mediated Cross-Talk

The transient receptor potential family V1 channel (TRPV1) is activated by multiple stimuli, including capsaicin, acid, endovanilloids, and heat (>42C). Post-translational modifications to TRPV1 result in dynamic changes to the sensitivity of receptor activation. We have previously demonstrated t...

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Detalhes bibliográficos
Main Authors: Rowan, Matthew P., Bierbower, Sonya M., Eskander, Michael A., Szteyn, Kalina, Por, Elaine D., Gomez, Ruben, Veldhuis, Nicholas, Bunnett, Nigel W., Jeske, Nathaniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973553/
https://ncbi.nlm.nih.gov/pubmed/24695785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093688
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