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Roles of conserved residues within the pre-NH(2)-terminal domain of herpes simplex virus 1 DNA polymerase in replication and latency in mice

The catalytic subunit of the herpes simplex virus 1 DNA polymerase (HSV-1 Pol) is essential for viral DNA synthesis and production of infectious virus in cell culture. While mutations that affect 5′–3′ polymerase activity have been evaluated in animal models of HSV-1 infection, mutations that affect...

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Bibliografski detalji
Glavni autori: Terrell, Shariya L., Pesola, Jean M., Coen, Donald M.
Format: Artigo
Jezik:Inglês
Izdano: Society for General Microbiology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973481/
https://ncbi.nlm.nih.gov/pubmed/24413420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.061903-0
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