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Roles of conserved residues within the pre-NH(2)-terminal domain of herpes simplex virus 1 DNA polymerase in replication and latency in mice
The catalytic subunit of the herpes simplex virus 1 DNA polymerase (HSV-1 Pol) is essential for viral DNA synthesis and production of infectious virus in cell culture. While mutations that affect 5′–3′ polymerase activity have been evaluated in animal models of HSV-1 infection, mutations that affect...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for General Microbiology
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973481/ https://ncbi.nlm.nih.gov/pubmed/24413420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.061903-0 |
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