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Expression of the herpes simplex virus type 1 latency-associated transcripts does not influence latency establishment of virus mutants deficient for neuronal replication

Herpes simplex virus type 1 establishes latency within neurons of the trigeminal ganglion. During latency, viral gene expression is largely restricted to the latency-associated transcripts (LATs), which, whilst not essential for any aspect of latency, function to suppress lytic gene expression and e...

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Autors principals: Nicoll, M. P., Efstathiou, S.
Format: Artigo
Idioma:Inglês
Publicat: Society for General Microbiology 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809108/
https://ncbi.nlm.nih.gov/pubmed/23907392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.056176-0
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