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Hypoxia Alters Ocular Drug Transporter Expression and Activity in Rat and Calf Models: Implications for Drug Delivery

PURPOSE: Chronic hypoxia, a key stimulus for neovascularization, has been implicated in the pathology of proliferative diabetic retinopathy, retinopathy of prematurity and wet age related macular degeneration. The aim of the present study was to determine the effect of chronic hypoxia on drug transp...

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Detalhes bibliográficos
Main Authors: Kadam, Rajendra S., Ramamoorthy, Preveen, LaFlamme, Daniel J., McKinsey, Timothy A., Kompella, Uday B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973437/
https://ncbi.nlm.nih.gov/pubmed/23607566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp3007133
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