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Influence of Drug Solubility and Lipophilicity on Transscleral Retinal Delivery of Six Corticosteroids

The influence of drug properties including solubility, lipophilicity, tissue partition coefficients, and in vitro transscleral permeability on ex vivo and in vivo transscleral delivery from corticosteroid suspensions was determined. Solubility, tissue/buffer partition coefficients for bovine sclera...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Thakur, Ashish, Kadam, Rajendra S., Kompella, Uday B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Pharmacology and Experimental Therapeutics 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082374/
https://ncbi.nlm.nih.gov/pubmed/21346004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.110.037408
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