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Brain Mitochondrial Drug Delivery: Influence of Drug Physicochemical Properties
PURPOSE: To determine the influence of drug physicochemical properties on brain mitochondrial delivery of 20 drugs at physiological pH. METHODS: The delivery of 8 cationic drugs (beta-blockers), 6 neutral drugs (corticosteroids), and 6 anionic drugs (non-steroidal anti-inflammatory drugs, NSAIDs) to...
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| Yayımlandı: | Pharm Res |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5510476/ https://ncbi.nlm.nih.gov/pubmed/21796482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-011-0532-4 |
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