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Amphiphilic drug interactions with model cellular membranes are influenced by lipid chain-melting temperature
Small-molecule amphiphilic species such as many drug molecules frequently exhibit low-to-negligible aqueous solubility, and generally have no identified transport proteins assisting their distribution, yet are able to rapidly penetrate significant distances into patient tissue and even cross the blo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973356/ https://ncbi.nlm.nih.gov/pubmed/24621813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2013.1062 |
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