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Dicer-related helicase 3 forms an obligate dimer for recognizing 22G-RNA

Dicer is a specialized nuclease that produces RNA molecules of specific lengths for use in gene silencing pathways. Dicer relies on the correct measurement of RNA target duplexes to generate products of specific lengths. It is thought that Dicer uses its multidomain architecture to calibrate RNA pro...

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Bibliografiske detaljer
Main Authors: Fitzgerald, Megan E., Vela, Adriana, Pyle, Anna Marie
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973318/
https://ncbi.nlm.nih.gov/pubmed/24435798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1383
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