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Dicer-related helicase 3 forms an obligate dimer for recognizing 22G-RNA

Dicer is a specialized nuclease that produces RNA molecules of specific lengths for use in gene silencing pathways. Dicer relies on the correct measurement of RNA target duplexes to generate products of specific lengths. It is thought that Dicer uses its multidomain architecture to calibrate RNA pro...

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Detalhes bibliográficos
Main Authors: Fitzgerald, Megan E., Vela, Adriana, Pyle, Anna Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973318/
https://ncbi.nlm.nih.gov/pubmed/24435798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1383
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