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Incorporation of thio-pseudoisocytosine into triplex-forming peptide nucleic acids for enhanced recognition of RNA duplexes

Peptide nucleic acids (PNAs) have been developed for applications in biotechnology and therapeutics. There is great potential in the development of chemically modified PNAs or other triplex-forming ligands that selectively bind to RNA duplexes, but not single-stranded regions, at near-physiological...

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Dettagli Bibliografici
Autori principali: Devi, Gitali, Yuan, Zhen, Lu, Yunpeng, Zhao, Yanli, Chen, Gang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
Soggetti:
RNA
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973316/
https://ncbi.nlm.nih.gov/pubmed/24423869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1367
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