PIP degron proteins, substrates of CRL4(Cdt2), and not PIP boxes, interfere with DNA polymerase η and κ focus formation on UV damage

Proliferating cell nuclear antigen (PCNA) is a well-known scaffold for many DNA replication and repair proteins, but how the switch between partners is regulated is currently unclear. Interaction with PCNA occurs via a domain known as a PCNA-Interacting Protein motif (PIP box). More recently, an add...

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Bibliografiska uppgifter
Huvudupphovsmän: Tsanov, Nikolay, Kermi, Chames, Coulombe, Philippe, Van der Laan, Siem, Hodroj, Dana, Maiorano, Domenico
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
Genome Integrity, Repair and Replication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973308/
https://ncbi.nlm.nih.gov/pubmed/24423875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1400
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