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Immortality, but not oncogenic transformation, of primary human cells leads to epigenetic reprogramming of DNA methylation and gene expression

Tumourigenic transformation of normal cells into cancer typically involves several steps resulting in acquisition of unlimited growth potential, evasion of apoptosis and non-responsiveness to growth inhibitory signals. Both genetic and epigenetic changes can contribute to cancer development and prog...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Gordon, Katrina, Clouaire, Thomas, Bao, Xun X., Kemp, Sadie E., Xenophontos, Maria, de Las Heras, Jose Ignacio, Stancheva, Irina
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973294/
https://ncbi.nlm.nih.gov/pubmed/24371281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1351
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