Mutational Signature of Aristolochic Acid Exposure as Revealed by Whole-Exome Sequencing

In humans, exposure to aristolochic acid (AA) is associated with urothelial carcinoma of the upper urinary tract (UTUC). Exome sequencing of UTUCs from 19 individuals with documented exposure to AA revealed a remarkably large number of somatic mutations and an unusual mutational signature attributab...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Hoang, Margaret L., Chen, Chung-Hsin, Sidorenko, Viktoriya S., He, Jian, Dickman, Kathleen G., Yun, Byeong Hwa, Moriya, Masaaki, Niknafs, Noushin, Douville, Christopher, Karchin, Rachel, Turesky, Robert J., Pu, Yeong-Shiau, Vogelstein, Bert, Papadopoulos, Nickolas, Grollman, Arthur P., Kinzler, Kenneth W., Rosenquist, Thomas A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973132/
https://ncbi.nlm.nih.gov/pubmed/23926200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3006200
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller