Pegylated IFN-α regulates hepatic gene expression through transient Jak/STAT activation

The use of pegylated interferon-α (pegIFN-α) has replaced unmodified recombinant IFN-α for the treatment of chronic viral hepatitis. While the superior antiviral efficacy of pegIFN-α is generally attributed to improved pharmacokinetic properties, the pharmacodynamic effects of pegIFN-α in the liver...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Dill, Michael T., Makowska, Zuzanna, Trincucci, Gaia, Gruber, Andreas J., Vogt, Julia E., Filipowicz, Magdalena, Calabrese, Diego, Krol, Ilona, Lau, Daryl T., Terracciano, Luigi, van Nimwegen, Erik, Roth, Volker, Heim, Markus H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973080/
https://ncbi.nlm.nih.gov/pubmed/24569457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70408
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares