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Autocrine IL-17A–IL-17RC neutrophil activation in fungal infections is regulated by IL-6, IL-23, RORγt and Dectin-2
Here we identified a population of bone marrow neutrophils that constitutively express RORγt and which can produce and respond to IL-17A (IL-17). IL-6, IL-23 and RORγt, but not T cells or NK cells, are required for IL-17 production in neutrophils. IL-6 and IL-23 induced IL-17RC and Dectin-2 expressi...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972892/ https://ncbi.nlm.nih.gov/pubmed/24362892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2797 |
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