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Recombination in mouse L cells between DNA introduced into cells and homologous chromosomal sequences.

In this paper, we show that DNA added to mouse L cells by the calcium phosphate method can be inserted into the genome of those cells by homologous recombination. The insertion event is detected because it reconstructs a functional thymidine kinase (tk) gene from two defective genes that share 320 b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lin, F L, Sperle, K, Sternberg, N
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1985
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC397267/
https://ncbi.nlm.nih.gov/pubmed/3856266
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