Recombination in mouse L cells between DNA introduced into cells and homologous chromosomal sequences.
In this paper, we show that DNA added to mouse L cells by the calcium phosphate method can be inserted into the genome of those cells by homologous recombination. The insertion event is detected because it reconstructs a functional thymidine kinase (tk) gene from two defective genes that share 320 b...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1985
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397267/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3856266/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.5.1391 |
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