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Periostin promotes renal cyst growth and interstitial fibrosis in polycystic kidney disease
In renal cystic diseases, sustained enlargement of fluid-filled cysts is associated with severe interstitial fibrosis and progressive loss of functioning nephrons. Periostin, a matricellular protein, is highly overexpressed in cyst-lining epithelial cells of autosomal dominant polycystic disease kid...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972302/ https://ncbi.nlm.nih.gov/pubmed/24284511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.488 |
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