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Overexpression of miR-125a in Myelodysplastic Syndrome CD34(+) Cells Modulates NF-κB Activation and Enhances Erythroid Differentiation Arrest
Myelodysplastic syndromes (MDS) are characterized by impaired proliferation and differentiation of hematopoietic stem cells. The participation of toll-like receptor (TLR)-mediated signaling in MDS is well documented. Increased TLR signaling leads to the constitutive activation of NF-κB, which mediat...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972113/ https://ncbi.nlm.nih.gov/pubmed/24690917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093404 |
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