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Fetal Cyclophosphamide Exposure Induces Testicular Cancer and Reduced Spermatogenesis and Ovarian Follicle Numbers in Mice

Exposure to radiation during fetal development induces testicular germ cell tumors (TGCT) and reduces spermatogenesis in mice. However, whether DNA damaging chemotherapeutic agents elicit these effects in mice remains unclear. Among such agents, cyclophosphamide (CP) is currently used to treat breas...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Comish, Paul B., Drumond, Ana Luiza, Kinnell, Hazel L., Anderson, Richard A., Matin, Angabin, Meistrich, Marvin L., Shetty, Gunapala
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972108/
https://ncbi.nlm.nih.gov/pubmed/24691397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093311
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