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Increasing Testicular Temperature by Exposure to Elevated Ambient Temperatures Restores Spermatogenesis in Adult Utp14b(jsd) mutant (jsd) mice

Because mutations in the human UTP14C gene are associated with male infertility, we sought to develop a method for fertility restoration in azoospermic mice with a mutation in the orthologous Utp14b(jsd) (jsd) gene that have spermatogonial arrest. The method is based on our observation that elevatio...

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Detalhes bibliográficos
Publicado no:Andrology
Main Authors: Comish, Paul B., Liang, Lai Yi, Yamauchi, Yasuhiro, Weng, Connie C., Shetty, Gunapala, Naff, Katherine A., Ward, Monika A., Meistrich, Marvin L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391977/
https://ncbi.nlm.nih.gov/pubmed/25303716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/andr.287
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