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p53-Dependent Apoptosis in the Inhibition of Spermatogonial Differentiation in Juvenile Spermatogonial Depletion (Utp14b(jsd)) Mice

In adult male mice homozygous for the juvenile spermatogonial depletion (Utp14b(jsd)) mutation in the Utp14b gene, type A spermatogonia proliferate, but in the presence of testosterone and at scrotal temperatures, these spermatogonia undergo apoptosis just before differentiation. In an attempt to de...

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Autors principals: Shetty, Gunapala, Shao, Shan H., Weng, Connie C. Y.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408807/
https://ncbi.nlm.nih.gov/pubmed/18356279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1338
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