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Identification and characterization of the carbapenem MM 4550 and its gene cluster in Streptomyces argenteolus ATCC 11009

Nearly 50 naturally-occurring carbapenem β-lactam antibiotics, most produced by Streptomyces, have been identified. The structural diversity of these compounds is limited to variance of the C-2 and C-6 side chains as well as the stereochemistry at C-5/C-6. These structural motifs are of interest bot...

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Détails bibliographiques
Auteurs principaux: Li, Rongfeng, Lloyd, Evan P., Moshos, Kristos A., Townsend, Craig. A
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972073/
https://ncbi.nlm.nih.gov/pubmed/24420617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300319
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