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Limited clearance of pre-existing amyloid plaques after intracerebral injection of Aβ antibodies in two mouse models of Alzheimer’s disease
Recent studies have demonstrated the potential utility of antibodies for the treatment of Alzheimer’s disease (AD). In transgenic mouse models of AD, peripheral and intracerebral administration of Aβ-specific antibodies reduces amyloid burdens to varied extents. The mechanism may involve clearance o...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972013/ https://ncbi.nlm.nih.gov/pubmed/18091561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/nen.0b013e31815f38d2 |
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