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Differential Ca(v)2.1 and Ca(v)2.3 channel inhibition by baclofen and α-conotoxin Vc1.1 via GABA(B) receptor activation
Neuronal Ca(v)2.1 (P/Q-type), Ca(v)2.2 (N-type), and Ca(v)2.3 (R-type) calcium channels contribute to synaptic transmission and are modulated through G protein–coupled receptor pathways. The analgesic α-conotoxin Vc1.1 acts through γ-aminobutyric acid type B (GABA(B)) receptors (GABA(B)Rs) to inhibi...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Rockefeller University Press
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3971658/ https://ncbi.nlm.nih.gov/pubmed/24688019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311104 |
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