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Xanthine Oxidase Inhibition by Febuxostat Attenuates Experimental Atherosclerosis in Mice
Atherosclerosis is a chronic inflammatory disease due to lipid deposition in the arterial wall. Multiple mechanisms participate in the inflammatory process, including oxidative stress. Xanthine oxidase (XO) is a major source of reactive oxygen species (ROS) and has been linked to the pathogenesis of...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3971401/ https://ncbi.nlm.nih.gov/pubmed/24686534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04554 |
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