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Comparison of methods to identify aberrant expression patterns in individual patients: augmenting our toolkit for precision medicine

BACKGROUND: Patient-specific aberrant expression patterns in conjunction with functional screening assays can guide elucidation of the cancer genome architecture and identification of therapeutic targets. Since most statistical methods for expression analysis are focused on differences between exper...

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Détails bibliographiques
Auteurs principaux: Bottomly, Daniel, Ryabinin, Peter A, Tyner, Jeffrey W, Chang, Bill H, Loriaux, Marc M, Druker, Brian J, McWeeney, Shannon K, Wilmot, Beth
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971350/
https://ncbi.nlm.nih.gov/pubmed/24286512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm509
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