Comparison of methods to identify aberrant expression patterns in individual patients: augmenting our toolkit for precision medicine

BACKGROUND: Patient-specific aberrant expression patterns in conjunction with functional screening assays can guide elucidation of the cancer genome architecture and identification of therapeutic targets. Since most statistical methods for expression analysis are focused on differences between exper...

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Hlavní autoři: Bottomly, Daniel, Ryabinin, Peter A, Tyner, Jeffrey W, Chang, Bill H, Loriaux, Marc M, Druker, Brian J, McWeeney, Shannon K, Wilmot, Beth
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971350/
https://ncbi.nlm.nih.gov/pubmed/24286512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm509
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