Comparison of methods to identify aberrant expression patterns in individual patients: augmenting our toolkit for precision medicine

BACKGROUND: Patient-specific aberrant expression patterns in conjunction with functional screening assays can guide elucidation of the cancer genome architecture and identification of therapeutic targets. Since most statistical methods for expression analysis are focused on differences between exper...

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Detalhes bibliográficos
Main Authors: Bottomly, Daniel, Ryabinin, Peter A, Tyner, Jeffrey W, Chang, Bill H, Loriaux, Marc M, Druker, Brian J, McWeeney, Shannon K, Wilmot, Beth
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971350/
https://ncbi.nlm.nih.gov/pubmed/24286512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm509
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