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Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells.

The tumor antigen p53 is overproduced in transformed cells of various species, including man. HL-60 is an exceptional human tumor cell line that does not express this protein. Hybridization of polyadenylylated mRNA of these cells with a human p53 cDNA probe (p53-H14), which we cloned, had indicated...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Wolf, D, Rotter, V
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1985
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397132/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2858093/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.3.790
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