Llwytho...

α1-antitrypsin deficiency and the hepatocytes - an elegans solution to drug discovery

Hepatocytes are metabolically active cells of the liver that play an important role in the biosynthesis of proteins including α1-antitrypsin. Mutations in the α1-antitrypsin gene can lead to protein misfolding, polymerization/aggregation and retention of protein within the endoplasmic reticulum of h...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: O’Reilly, Linda P., Perlmutter, David H., Silverman, Gary A., Pak, Stephen C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970812/
https://ncbi.nlm.nih.gov/pubmed/24355812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2013.12.006
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