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Hippocampal molecular mechanisms involved in the enhancement of fear extinction caused by exposure to novelty

Exposure to a novel environment enhances the extinction of contextual fear. This has been explained by tagging of the hippocampal synapses used in extinction, followed by capture of proteins from the synapses that process novelty. The effect is blocked by the inhibition of hippocampal protein synthe...

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Autori principali: de Carvalho Myskiw, Jociane, Furini, Cristiane Regina Guerino, Benetti, Fernando, Izquierdo, Ivan
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970530/
https://ncbi.nlm.nih.gov/pubmed/24591622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400423111
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