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Hippocampal molecular mechanisms involved in the enhancement of fear extinction caused by exposure to novelty

Exposure to a novel environment enhances the extinction of contextual fear. This has been explained by tagging of the hippocampal synapses used in extinction, followed by capture of proteins from the synapses that process novelty. The effect is blocked by the inhibition of hippocampal protein synthe...

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Detalhes bibliográficos
Main Authors: de Carvalho Myskiw, Jociane, Furini, Cristiane Regina Guerino, Benetti, Fernando, Izquierdo, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970530/
https://ncbi.nlm.nih.gov/pubmed/24591622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400423111
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