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Facilitation of fear extinction by novelty depends on dopamine acting on D1-subtype dopamine receptors in hippocampus

Extinction is the learned inhibition of retrieval. Recently it was shown that a brief exposure to a novel environment enhances the extinction of contextual fear in rats, an effect explainable by a synaptic tagging-and-capture process. Here we examine whether this also happens with the extinction of...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Menezes, Jefferson, Alves, Niége, Borges, Sidnei, Roehrs, Rafael, de Carvalho Myskiw, Jociane, Furini, Cristiane Regina Guerino, Izquierdo, Ivan, Mello-Carpes, Pâmela B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386331/
https://ncbi.nlm.nih.gov/pubmed/25775606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502295112
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