Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation

Cell survival after DNA damage relies on DNA repair, the abrogation of which causes genomic instability and development of cancer. However, defective DNA repair in cancer cells can be exploited for cancer therapy using DNA-damaging agents. DNA double-strand breaks are the major lethal lesions induce...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Gasparini, Pierluigi, Lovat, Francesca, Fassan, Matteo, Casadei, Lucia, Cascione, Luciano, Jacob, Naduparambil K., Carasi, Stefania, Palmieri, Dario, Costinean, Stefan, Shapiro, Charles L., Huebner, Kay, Croce, Carlo M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2014
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970505/
https://ncbi.nlm.nih.gov/pubmed/24616504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402604111
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