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Structure-Function Relationships of ErbB RTKs in the Plasma Membrane of Living Cells

We review the states of the ErbB family of receptor tyrosine kinases (RTKs), primarily the EGF receptor (EGFR, ErbB1, HER1) and the orphan receptor ErbB2 as they exist in living mammalian cells, focusing on four main aspects: (1) aggregation state and distribution in the plasma membrane; (2) conform...

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Bibliografische gegevens
Hoofdauteurs: Arndt-Jovin, Donna J., Botelho, Michelle G., Jovin, Thomas M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970415/
https://ncbi.nlm.nih.gov/pubmed/24691959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a008961
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