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Structure-Function Relationships of ErbB RTKs in the Plasma Membrane of Living Cells
We review the states of the ErbB family of receptor tyrosine kinases (RTKs), primarily the EGF receptor (EGFR, ErbB1, HER1) and the orphan receptor ErbB2 as they exist in living mammalian cells, focusing on four main aspects: (1) aggregation state and distribution in the plasma membrane; (2) conform...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3970415/ https://ncbi.nlm.nih.gov/pubmed/24691959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a008961 |
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