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Priming of human mitochondrial DNA replication occurs at the light-strand promoter.

Individual promoters for transcription of each strand of human mtDNA are located near the origin of heavy-strand DNA replication in the displacement-loop region. Initiation of heavy-strand synthesis represents the first event in mtDNA replication. Analyses of the 5' and 3' map positions of...

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Dettagli Bibliografici
Autori principali: Chang, D D, Clayton, D A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1985
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC397036/
https://ncbi.nlm.nih.gov/pubmed/2982153
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