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Replication of mitochondrial DNA occurs by strand displacement with alternative light-strand origins, not via a strand-coupled mechanism

The established strand-displacement model for mammalian mitochondrial DNA (mtDNA) replication has recently been questioned in light of new data using two-dimensional (2D) agarose gel electrophoresis. It has been proposed that a synchronous, strand-coupled mode of replication occurs in tissues, there...

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Bibliografiska uppgifter
Huvudupphovsmän: Brown, Timothy A., Cecconi, Ciro, Tkachuk, Ariana N., Bustamante, Carlos, Clayton, David A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2005
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1257401/
https://ncbi.nlm.nih.gov/pubmed/16230534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1352105
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