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Replication-competent human mitochondrial DNA lacking the heavy-strand promoter region.

We identified two patients with progressive external ophthalmoplegia, a mitochondrial disease, who harbored a population of partially deleted mitochondrial DNA (mtDNA) with unusual properties. These molecules were deleted from mtDNA positions 548 to 4,442 and encompassed not only rRNA sequences but...

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Detalhes bibliográficos
Main Authors: Moraes, C T, Andreetta, F, Bonilla, E, Shanske, S, DiMauro, S, Schon, E A
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC369459/
https://ncbi.nlm.nih.gov/pubmed/1996112
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